Juviderm®
Juviderm® ULTRA 2
An injectable implant designed to fill moderately severe sagging facial skin by injecting the drug into the middle layers of the dermis, as well as to correct the contour of the lips. It is used to eliminate shallow wrinkles, especially at the corners of the eyes and those lying in close proximity to the surface of the skin.
Juviderm® ULTRA 3
An injection implant designed to fill moderate and deep sagging facial skin by injecting the drug into the middle and/or deep layers of the dermis, as well as to increase the volume of the lips and correct their contour. It is most often used to smooth out medium-deep and deep nasolabial folds.
Juviderm® ULTRA 4
An injection implant designed to fill deep sagging facial skin by injecting the drug into the deep layers of the dermis, as well as to increase the volume of lips and cheekbones. Used to fill deep wrinkles using injections, as well as to increase the volume of lips and cheekbones.
Juviderm® ULTRA SMILE
Designed specifically for correcting lip volume and contour.
Juviderm® VOLBELLA™ with Lidocaine
The Juviderm® VOLBELLA™ with Lidocaine intradermal implant is a sterile, pyrogen-free, physiological gel of cross-linked hyaluronic acid using VYCROSS™ technology of non-animal origin. Contains 15 mg/ml hyaluronic acid and 3 mg/ml lidocaine hydrochloride.
Created for:
- plastic surgery of superficial wrinkles and moderately pronounced sagging of the facial skin, which occurs, in particular, with its premature aging;
- increasing the volume of the lips and correcting their contour in order to correct such structural defects as lip asymmetry, unevenness of their contour, loss of lip volume, etc.
Juviderm® HYDRATE™
Sterile, pyrogen-free and physiological solution of hyaluronic acid of non-animal origin. Contains 13.5 mg hyaluronic acid, 9 mg mannitol, phosphate buffer pH 7.2 to a final weight of 1 g.
Designed to increase skin hydration and elasticity by repeated injection of the drug into the area of the dermal-epidermal junction of the skin and the surface layer of the dermis.
Definition and Features
The main purpose of medicinal cosmetics is prevention and treatment, and this determines the special requirements for it. The requirements for medicinal cosmetics are the same as for medical drugs.
Medicinal products can only be used after clinical trials have been completed in a laboratory on sick people.
Therapeutic cosmetics are intended for people with sensitive or problematic skin. Since the cause of skin diseases is usually hidden inside the body, medicinal cosmetics are aimed not only at eliminating external signs of the disease, but also have a general therapeutic effect.
Unlike conventional decorative cosmetics, medicinal ones affect the top layer of the skin and are able to penetrate into its deeper layers. With their help you can carry out professional facial care.
Treatment and prevention of facial skin diseases are carried out using substances contained in the medicinal product. The composition of medicinal cosmetic products for the face includes biologically active, auxiliary, organic and inorganic substances.
Read about the rules for automatic facial cleansing by following the link.
Together, they have a healing effect on the skin of the face, since some substances have a positive effect on the surface layer of the dermis, while others penetrate into its cells.
Substances contained in medicinal products for facial skin:
- Vitamins. Their role is important in the biochemical processes of the body and normal metabolism. The presence of vitamin C in the body accelerates the restoration and healing processes, under its influence paleness and dryness of the skin are eliminated. Vitamin C is one of the main components of biocreams and creams for the skin around the eyes. Vitamin P prevents diseases such as psoriasis, chronic dermatosis, and demodicosis. Vitamin B2 ensures normal redox processes in skin cells and prevents the appearance of acne. One of the most common vitamins in cosmetic and dermatological preparations is Vitamin A. It takes an active part in ensuring the integrity of the skin structure and restores the healthy functions of the epidermis. Vitamin F prevents dryness and thickening of the skin, promotes the formation of new cells in place of dead ones. Included in many nourishing and restorative creams.
- Essential oils are plant components containing terpents, esters, alcohols, aldehydes, and phenol. Essential oils are characterized by their specific smell. The benefits of essential oils for facial skin include bactericidal, analgesic, anti-inflammatory, and soothing properties. Essential oils are included in anti-aging products because they are good antioxidants.
- Minerals. Sulfur prevents skin inflammation. Potassium is responsible for regulating humidity levels. Sodium helps nutrients penetrate and be absorbed. Magnesium prevents allergic reactions and slows down the aging process. Aluminum has smoothing and tightening effects on the skin. Black mud containing kaolin, quartz, mica is effective in cleansing the skin.
- Hormones – estrogens and androgens. Therapeutic substances with hormones are used for dysfunction of the gonads, as a result of which acne appears on the face.
- Animal products : honey, royal jelly, propolis, beeswax, mumiyo. These products have rejuvenating, tonic, and nourishing properties.
Teosyal®
The TEOXANE laboratory provides a wide range of unique products for contour correction based on 100% hyaluronic acid of non-animal origin.
Teosyal fillers are products of the highest quality. Three main characteristics that guarantee high patient and doctor satisfaction with the result:
- efficiency
- safety
- long lasting result
Purpose of filler and contouring procedure? restore lost volumes of the skin of the face, neck, décolleté, and hands.
The classic line of Teosyal fillers is the most complete range of preparations with various viscoelastic properties for intradermal, subcutaneous and external injection. All drugs are presented in two versions - with lidocaine (PureSense filler line) and without lidocaine.
In addition to products of various densities, the line includes true volumizers (Ultra Deep, Ultimate), capable of recreating volume in the area of the cheekbones and chin. There are also several unique products designed specifically for the correction of certain areas: the infraorbital zone (Redensity 2) and lips (Teosyal Kiss).
- restoration of volume in the area of wrinkles, elimination of nasolabial folds and wrinkles of sadness, forehead and eyebrows, “crow’s feet”, purse-string wrinkles, etc.
- correction of the shape and volume of the lips, corners of the mouth
- adding volume to cheekbones and chin
- correction of dark circles under the eyes - nasolacrimal and palpebromalar grooves
- restoration of lost earlobe volume
- face oval correction
- correction of the shape and elimination of deformities of the nose (wings, back and tip)
- eyebrow lifting, correction of their shape and volume
- correction of scars, post-acne, stretch marks
- intimate plastic surgery
Hyaluronic acid, included in preparations for the correction of wrinkles and nasolabial folds, is part of connective, epithelial and nervous tissue: the human body contains about 15 grams of this substance. Without it, a number of the most important biochemical processes occurring in the human body are impossible. Hyaluronic acid is a polysaccharide that, under the action of enzymes, hyaluronidases, is decomposed into simpler compounds. Therefore, the validity period of injections of fillers and preparations containing hyaluronic acid is 6 – 9 (sometimes 12) months, after which the procedure for correcting nasolabial folds must be repeated.
Teosyal® Meso
Impact area: Rejuvenation of face, neck, décolleté area
Indications: Moisturizing, revitalization of the skin of the face, neck, décolleté and back of the hand
Duration of action: 2-3 months
TEOSYAL Meso is a preparation based on non-reticular hyaluronic acid.
The biorevitalization drug provides an optimal level of dermis moisture and improves skin tone. For good absorption, the molecular weight of hyaluronic acid corresponds to the mass of this substance in the skin (1 million daltons).
The drug is injected into the superficial layer of the dermis.
It is recommended to carry out 2-3 biorevitalization procedures with an interval of 3 weeks, then once every 2-3 months.
Teosyal®MesoExpert
Indications: Regeneration, moisturizing and preventing the formation of wrinkles, decreased skin tone
Duration of action: 2-3 months
A preparation based on hyaluronic acid for skin biorevitalization. It has anti-inflammatory and antioxidant effects, allows you to restructure and restore the skin, stimulates metabolism and regulates the process of energy formation.
Includes a full range of ingredients necessary for skin regeneration - antioxidants, amino acids, vitamin B6 and minerals (zinc and copper).
Teosyal®PureSense Redensity I
Indications: biorevitalization, moisturizing the skin of the neck, face, back of the hand and décolleté.
Duration of action: 2-3 months
The TEOXANE laboratory produces the drug for biorevitalization and mesotherapy TEOSYAL PureSense Redensity I.
The innovative formula of TEOSYAL PureSense Redensity I is based on hyaluronic acid and carefully selected components that are natural structural elements of the skin. The synergistic effect of these components is aimed at restoring antioxidant protection and strengthening the dermis.
Teosyal®PureSense Redensity II
Treatment area: Crow's feet, Nasolacrimal trough
Volume capacity: 1
Indications: Correction of nasolacrimal and palpebromalar grooves
Duration of validity: 12 months
1. Innovative and synergistic 3 in 1 formula combining natural ingredients:
- Hyaluronic acid 15 mg/g. A combination of reticulated and non-reticulated hyaluronic acid.
- Dermorestructuring complex: 8 amino acids, 3 antioxidants, 2 minerals and 1 vitamin.
- Lidocaine.
2. Low hygroscopicity. To avoid swelling after injection of gel in an amount of <0.5 ml on one side
3. Ideal viscoelasticity: high distribution ability. For maximum ease of injection (81%*) and distribution (100%*).
4. Lightweight gel that exerts low pressure on tissue. To minimize the risk of swelling.
Teosyal®PureSense Ultimate / TEOSYAL Ultimate
Volume capacity: 6
Indications: Remodeling of facial contours, creating volume
Duration of action: 12-18 months
TEOSYAL Ultimate is an injectable implant with an intense filling effect, first presented in exclusive 3 ml syringes, which is an ideal solution for restoring the fatty frame of the face. An injection of 3 ml of the drug improves facial contours and creates volume in just one procedure.
Level of drug administration: injections are carried out supraperiostally or deep into the subcutaneous fat, but never intradermally.
With TEOSYAL Ultimate, 1 or 2 injections of 3 ml are enough to obtain optimal correction for 18 months.
Differences between TEOSYAL Ultimate and TEOSYAL PureSense Ultimate fillers
The PereSense line contains lidocaine, which ensures a painless procedure.
Teosyal®PureSense Kiss / TEOSYAL Kiss
Treatment area: Lip volume, Lip corners, Lip contour
Volume capacity: 5
Indications: Correction of contours, wrinkles around the lips, increasing lip volume
Duration of action: 6-9 months
TEOSYAL Kiss is a highly reticular product that guarantees lasting results in increasing lip volume. The drug is used for contouring and increasing lip volume, restoring normal levels of moisture and filling wrinkles in the corners of the mouth. The effect accumulates with each procedure. An additional procedure for biorevitalization or lip augmentation is recommended after 6-9 months.
Contraindications
The use of drugs for lip contouring has a number of contraindications. Before the contouring procedure, obtain a complete medical history and ensure that the patient does not have any skin lesions. If at least one of the listed signs is observed, lip contour correction is contraindicated:
- hypersensitivity to hyaluronic acid;
- disruption of the immune system;
- various types of infection at the injection sites;
- general diseases in the acute stage;
- pregnancy and breastfeeding;
- autoimmune diseases;
- herpes.
To prolong the result of the lip augmentation or lip modeling procedure, it is prohibited to take aspirin, anti-inflammatory and anticoagulant drugs in large doses for 7 days after correction. In the first days after contouring, sudden transitions from cold to heat and, conversely, walking in the open sun and visiting a solarium are not recommended.
Differences between TEOSYAL Kiss and TEOSYAL PureSense Kiss
Lidocaine, which is part of TEOSYAL PureSense Kiss, makes the procedure for correcting the shape and volume of the lips painless for the patient.
Teosyal®PureSense Ultra Deep / TEOSYAL Ultra Deep
Impact area: Cheekbones and cheeks, Oval face
Volume capacity: 5
Indications: Volumetric remodeling, deep wrinkles on thick skin
Duration of action: 6-12 months
The filler is used to increase lip volume and remove nasolabial folds and deep wrinkles.
A preparation with hyaluronic acid, intended for contouring and lip augmentation, is injected into the deep layer of the dermis or subcutaneous tissue.
An additional procedure is recommended after 9-12 months.
The effect accumulates with each procedure.
Differences between TEOSYAL Ultra Deep and TEOSYAL PureSense Ultra Deep
The PureSense line contains lidocaine, which means no additional local anesthesia is required during the procedure.
Teosyal®PureSense First Lines / TEOSYAL First Lines
Treatment area: Crow's feet, Nasolabial folds
Volume capacity: 1
Indications: Correction of fine wrinkle lines, preoral lines, crow's feet, lines in the forehead and between the eyebrows
Duration of action: 2-3 months
For the correction of superficial wrinkles.
The filler allows you to remove nasolabial folds, correct superficial wrinkles in areas with thin skin, “crow’s feet” and wrinkles above the lip.
The drug for contouring is injected into the superficial layer of the dermis.
A repeat biorevitalization or contouring procedure is recommended after 6-9 months.
The effect accumulates with each procedure.
Differences between TEOSYAL First Lines and TEOSYAL PureSense First Lines
The anesthetic lidocaine included in the TEOSYAL PureSense First Lines filler makes injections painless.
Teosyal®PureSense Deep Lines / TEOSYAL Deep Lines
Treatment area: Nasolabial folds, Marionette lines
Volume capacity: 4
Indications: Deep wrinkles, correction of pronounced nasolabial folds, “marionette lines”
Duration of action: 6-9 months
Deep recovery.
The filler allows you to remove nasolabial folds and deep wrinkles. A product based on hyaluronic acid is injected into the deep layer of the dermis.
A repeat procedure to eliminate deep nasolabial folds and wrinkles is recommended after 6-9 months. The effect accumulates with each contouring procedure.
Differences between TEOSYAL Deep Lines and TEOSYAL PureSense Deep Lines fillers
TEOSYAL PureSense Deep Lines contains lidocaine, making the procedure painless for the patient.
Teosyal®Touch Up
Volume capacity: 3
Indications: Support sessions for all areas of the face
Duration of action: 6-9 months
It differs from TEOSYAL Global Action filler only in packaging.
Allows you to eliminate skin and linear, as well as nasolabial folds. Used for repeated biorevitalization procedures and as an addition to other products in the line.
Teosyal®PureSense Global Action / TEOSYAL Global Action
Treatment area: Perioral wrinkles, Eyebrow wrinkles, Lip volume, Corners of lips, Nasolabial folds, Frontal wrinkles, Lip contour
Volume capacity: 3
Indications: Correction of medium depth wrinkles, glabellar area, preoral wrinkles, nasolabial folds, increasing lip volume and correction of lip contours
Duration of action: 6 months
A drug based on hyaluronic acid of non-animal origin is recommended for filling linear and skin wrinkles, contouring nasolabial folds of weak and moderate severity.
The filler is injected into the nasolabial fold or wrinkle into the middle layer of the dermis.
A repeat contouring procedure is recommended after 6-9 months.
The effect accumulates with each procedure.
Differences between TEOSYAL Global Action and TEOSYAL PureSense Global Action fillers
The PureSense line product contains the anesthetic substance lidocaine, which contributes to the comfort of the procedure for the patient.
Products from famous brands
Many leading countries of the world are engaged in the production of preparations for body and face rejuvenation. Mixtures have different costs, composition and quality.
Mesococktails from domestic brands are affordable, however, they have high quality indicators in comparison with competing manufacturers from other countries.
You can choose based on the woman’s individual preferences or the specifics of the cosmetologist’s work. Prestigious cosmetic centers do not accept the use of cheap formulations, which correctly prevents adverse consequences.
Russian
In our country, the production of anti-aging serums is not well established. However, a decisive step towards aesthetics and youth was taken by the Skinasil company, which began producing mesotherapy drugs in 2007.
The most popular mixtures of this brand are:
- Kolelast Complex. Created on the basis of collagen and elastin hydrolyzate. Properly nourishes and moisturizes the skin, increases its elasticity.
The solution is indicated for reduced tone and elasticity of the dermis, as well as for the presence of deep wrinkles on the face and neck.The recommended course consists of 6 procedures with an interval of 1 week, followed by two maintenance procedures with a break of two weeks, then injections are performed once a month. The cost of one procedure is 2 - 4 thousand rubles.
- Kaviar .
The serum is made from an extract of sturgeon caviar. The composition is recommended for pronounced age-related changes in the skin - withering, loss of elasticity, disturbance of relief, folds, increased dryness, paleness of the face. It has an antioxidant effect, supplies the skin with nutrients, and restores its natural properties. The recommended course is 4 procedures once every two weeks. The price per session is about 5-6 thousand rubles. - Gibilan .
The main active ingredient is ginkgo biloba extract. It is used in cosmetology as vascular mesotherapy or as part of other cocktails. Improves blood circulation, changes skin color, eliminates spider veins and swelling. Has an antioxidant effect, supports and restores vascular health. Sessions are conducted 5–10 times with a break after each of 7 days. The price of one rejuvenation zone varies between 3-4 thousand rubles.
Japanese
In the domestic market of cosmetic products, preparations for facial rejuvenation are represented by the Japanese brand Sakura. They always contain collagen, elastin and glycosaminoglycan.
The following serums are worth highlighting:
- Complex Sakura - intended for women under 30 years old.
- Sakura EJI complex - recommended for mature patients;
- Sakura EJI Extra complex - used after 45 years.
All three drugs direct their action towards high-quality lifting, combating age-related changes and saturating the skin with all the necessary microelements and vitamins.
Thanks to placenta extract, blood circulation improves and age spots disappear. The skin receives proper hydration, which helps smooth out unevenness.
The course of facial mesotherapy using Sakura serums is 8–9 sessions with an interval of 12 days. Rejuvenation can be repeated after 12–15 months. The cost of 1 procedure is 10 thousand rubles.
Korean
Korean cosmetics companies are meticulous about aesthetics. Korean cosmetics are distinguished by their miraculous properties, which can confidently be attributed to facial rejuvenation using mesotherapy.
The manufacturer Caregen co ltd decided to use its innovative technologies to create mesopreparations:
- Dermaheal SR. The drug contains minerals, vitamins, copper tripendide-1, and substances with a bioregulatory effect.
Indications include premature aging, dry skin, sagging and the presence of enlarged pores.The serum eliminates wrinkles, stabilizes fluid balance, and increases elasticity. The course is 5–7 sessions with a break of 10 days. The cost of the procedure starts from 4 thousand rubles.
- Dermaheal Stem C'rum SR. The composition contains epidermal growth factors and complex amino acids. The product is indicated for use in the presence of facial wrinkles, high levels of skin sagging and signs of aging.
The mixture is a two-phase serum, which, thanks to the presence of a nutrient medium, stimulates the skin to regenerate, ensures the growth of stem cells, eliminates wrinkles and rejuvenates the dermis.7 mesotherapy sessions using this drug are recommended. The break between sessions should not be less than 1 week. The cost varies between 6 thousand rubles.
American
The USA is a leading manufacturer of mesomedicines, distinguished by their quality and effectiveness.
The following representatives gained popularity:
- Meso-Xanthin .
The active ingredients in the drug include hyaluronic acid and fucoxanthin. The latter substance can stimulate the activity of the most important skin cells. The serum is used as a prophylactic agent during the aging stage. Whitens facial skin, makes the relief smooth, eliminates pigmentation. Experts tend to believe that 4 sessions are effective. The average price for the procedure is 10–12 thousand rubles. - MesoWharton .
It is one of the newest injectable drugs and is considered the best anti-aging product for patients over 40 years of age. The drug is based on hyarulonic acid and a synthetic analogue of a natural peptide. This complex allows you to stimulate the activity of stem cells. Indications include loss of elasticity, pigmentation, dehydration, deep wrinkles, irregular facial contours, and scar removal. The course consists of 5 - 8 sessions with an interval of 10 days. The Mezovarton procedure costs approximately 20 thousand rubles.
Italian
Italy also distinguished itself with quite worthy drugs for the correction of facial defects:
- BioAgeDNA .
At its core, it is a highly polymeric non-cleotide of DNA of dermal cells in combination with Tocopherol. This combination allows you to stimulate DNA cells to regenerate. The drug is designed to smooth the skin, protect against free radicals and provide powerful hydration. 1 session every 14 days is recommended. The average price for the procedure is 3 thousand rubles. - Foto-ageElastase .
It is considered the best skin protector against photoaging. Contains: organic silicon, plant substances, elastin. The drug is intended to smooth out wrinkles and eliminate serious defects such as scars and cicatrices. Provides intense hydration, improves blood flow, and supplies cells with oxygen. Cosmetologists prescribe 1 session every 14 days for 2 months. Price: 4,800 rubles.
Spanish
The meso cocktails of Spain were distinguished by their proper quality. Cosmetic products are distinguished by their effectiveness, safety and are used with confidence in prestigious salons of our country.
The most popular drug is LighteningXtra . The composition includes ascorbic acid, peptides, licorice root extract, ericoline, chromabrite. The combination of substances allows you to regulate proper cellular function.
The drug is most often prescribed for skin pigmentation. The action of the substances is aimed at eliminating freckles, spots of various sizes and shades, as well as changing the pathological color of the skin.
General course - 1 procedure per week for 30 days. Price from 3 thousand rubles.
French
France also has its leader in the mesomedicines market. Embrioblast Filorga mesococktail has won the trust of patients .
It has proven itself in the prevention of dermal aging in middle-aged patients. It has a pronounced effect of smoothing the relief and folds of various sizes and depths.
The drug is unique in its kind and manufactured by the leading French company Filorga. In addition to the main composition of active ingredients, the drug is distinguished by the presence of sheep embryonic cells.
After injection with this cocktail, important skin cells begin intensive work on rejuvenation. Thus, wrinkles are completely smoothed out, and the lumpy mesh disappears.
To learn how to choose preparations for facial mesotherapy, watch the video.
Restylane®
The Restylane® family of products was developed to ensure that individuality and beauty are achieved in a completely natural way. They are designed to improve the appearance by rejuvenating the skin, smoothing folds and wrinkles, giving additional volume to tissues and improving facial contours. A wide range of possibilities allows you to carry out procedures, fully taking into account the characteristics of each patient.
Restylane is manufactured using patented NASHA™ technology (Q-MED), which minimally stabilizes hyaluronic acid to produce a dense gel. Raw materials are obtained from non-animal sources to ensure biocompatibility of the drugs with tissue after administration. Restylane is a biodegradable drug, which over time, during the life of the body, breaks down and is naturally eliminated from it.
Safety is a very important aspect for patients. RESTYLANE received FDA approval following successful safety, efficacy and comparative clinical studies. Restylane is manufactured in Sweden by Q-Med AB.
Medicinal Cosmetic Products – Compliance with Federal Law.
Medicinal Cosmetic Products – Compliance with Federal Law.
Cosmetology is a field of clinical medicine that studies the nature and mechanism of the occurrence of cosmetic defects and develops methods for their elimination, camouflage and prevention.
The main issues of modern clinical cosmetology are the improvement of methods of diagnosis, prevention and treatment of cosmetic imperfections and skin diseases, the development of cosmetic geriatrics, pediatric cosmetic surgery, and cosmetic rehabilitation.
Industrial cosmetology studies, creates formulations and produces cosmetic preparations designed for the mass consumer and necessarily containing ingredients that are not potent and harmless to human health.
Clinical (medical) cosmetology mainly deals with individual cases, which often require a thorough study by a cosmetologist of the patient’s physiological state, and therefore there is a need for an individual approach to the formulation of certain cosmetic preparations.
It should be noted that the main feature of modern cosmetics production is its approach to the pharmaceutical industry, because the limited range of cosmetic raw materials has recently been significantly expanded with a range of highly active substances that have pharmacological effects.
Since the Federal Law “On the Circulation of Medicines” , manufacturers and sellers of cosmetic products in Russia must learn to live in a new way, taking into account the new legislative documents that regulate the circulation of medicines. Preparations for injection techniques and formulations with chemical acids can no longer be classified as cosmetics. These are cosmetic, i.e. medical drugs.
Definition of what a medicinal product is in Federal Law No. 61 “On the Circulation of Medicines” and medical devices (FZ-323):
Medicines are substances or their combinations that come into contact with the human body, penetrate organs, tissues of the human body, used for prevention, diagnosis (except for substances or their combinations that do not come into contact with the human body), treatment of diseases, rehabilitation, and received from blood, blood plasma, organs, tissues of the human or animal body, plants, minerals by synthesis methods or using biological technologies.
Medical product - any instruments, devices, instruments, equipment, materials and other products used for medical purposes separately or in combination with each other, as well as together with other accessories necessary for the use of these products for their intended purpose, including special software, and intended manufacturer for the prevention, diagnosis, treatment and medical rehabilitation of diseases, monitoring the condition of the human body, conducting medical research, restoration, replacement, changing the anatomical structure or physiological functions of the body, preventing or terminating pregnancy, the functional purpose of which is not realized through pharmacological, immunological, genetic or metabolic effects on the human body. Medical products can be recognized as interchangeable if they are comparable in functionality, quality and technical characteristics and are capable of replacing each other.
Since a cosmetic product is a drug, product manufacturers and suppliers must consider quality, effectiveness and safety strictly in accordance with the law, and not just for marketing messages to the client.
The quality of the medicinal product must comply with the requirements of the pharmacopoeial monograph or, in the absence of one, regulatory documentation or regulatory document.
In terms of safety, the characteristics of a medicinal product should be based on a comparative analysis of its effectiveness and the risk of harm to health.
By effectiveness - a characteristic of the degree of positive effect of a drug on the course, duration of the disease or its prevention, rehabilitation.
From the definition of “circulation of medicinal products” it becomes clear that different entities are involved in the circulation of medicinal products - from manufacturers, distributors of cosmetic products to managers of beauty salons and cosmetologists.
Circulation of medicinal products is development, preclinical studies, clinical studies, examination, state registration, standardization and quality control, production, manufacturing, storage, transportation, import into the territory of the Russian Federation, export from the territory of the Russian Federation, advertising, release, sale, transfer , use, destruction of medicines.
The relations of all entities involved in circulation are regulated by Federal Law No. 61 “On the Circulation of Medicines”.
It should be noted that now almost all companies - suppliers of cosmetic products - can be closed by a strong-willed political decision in one day only because today they are not subjects of pharmaceutical activity.
What is pharmaceutical activity?
This is an activity that includes wholesale trade in medicines, their storage, transportation and (or) retail trade in medicines, their dispensing, storage, transportation, and manufacturing of medicines.
But companies that supply cosmetic drugs are, according to the law, an organization of wholesale trade in medicines - an organization that carries out wholesale trade in medicines, their storage, transportation in accordance with the requirements of this Federal Law.
Order of the Ministry of Health and Social Development of the Russian Federation dated December 28, 2010 N 1222n approved the Rules for the wholesale trade of medicines for medical use for such supplier companies.
Only organizations that have a license for pharmaceutical activities with the obligatory indication “wholesale trade of medicines” on the territory of Russia have the legal right to sell medicines or transfer them in the manner established by the legislation of the Russian Federation to individual entrepreneurs or medical organizations. They, in turn, must have a license for pharmaceutical activities or a license for medical activities. And the organization itself is obliged to post a copy of the license for pharmaceutical activities for review.
The Rules prescribe the procedure for the sale of cosmetics (for cosmetic medicinal products).
An accompanying document is issued for medicines containing information:
- the date of execution of the accompanying document;
- on the name of the medicinal product (international nonproprietary name of the medicinal product and trade name of the medicinal product), expiration date and batch number;
- about the manufacturer of the medicinal product, indicating the name and location of the manufacturer;
- about the number of packages;
- about the supplier (taxpayer identification number, full name of the supplier, its location);
- about the buyer (taxpayer identification number, full name of the buyer, his location);
- about the official who drew up the accompanying document (position, full name).
- The document must be certified by the signature of the official who compiled the accompanying document, the seal of the organization or an information barcode and the seal of the organization.
Concepts used:
- A batch of a medicinal product is the quantity of a medicinal product produced as a result of one technological cycle by its manufacturer;
- Registration certificate is a document confirming the fact of state registration of a medicinal product;
- Registration number is a code designation assigned to a medicinal product during its state registration.
Bodies of Roszdravnadzor and the prosecutor's office, when checking the rules for the use of cosmetic preparations in beauty salons and cosmetology clinics, are already asking the heads of beauty industry enterprises to provide these documents. As a rule, it turns out that there is no such document, just as there is no license for the right to wholesale medicine from the company where the salon or clinic purchases fillers, botulinum toxin preparations or peeling products.
What exactly, today, of the many cosmetic preparations, is a medicinal product.
Preparations for mesotherapy, for contouring, as well as botulinum toxin preparations are medicines.
While botulinum toxin preparations are, for the most part, registered as medicines, mesotherapy preparations are generally imported as lotions for external use.
Chemical peels (both medium and deep) are also medicinal products, but are sold as cosmetic products without registration.
Preparations containing hyaluronic acid are used in the treatment of joints and burns, and they are also administered to rejuvenate the skin. But, for the most part, they do not have the appropriate documents.
Preparations for mesotherapy are mainly sold and imported into the Russian Federation as ampoule cosmetics for external use, but are used for subcutaneous administration.
Currently in the state. the register of medicines posted on the official portal of the Ministry of Health and Social Development of Russia includes drugs containing botulinum neurotoxin type A (Xeomin, Botox, Dysport, Lantox, etc.) as an active ingredient, as well as hyaluronic acid (Hyalgan Phidia). In addition to medical practice, these drugs are widely used in cosmetology.
The topic of registration is also addressed by Order of the Ministry of Health and Social Development of the Russian Federation N 321n “On the registration certificate of a medicinal product for medical use,” which explains to drug market participants that the registration certificate of a medicinal product for medical use may have annexes that are an integral part of it.
Sources:
- Federal Law No. 61 and No. 323
- Order of the Ministry of Health and Social Development of the Russian Federation N 321n
- https://www.1nep.ru/
Educational phone numbers : 8-812-248-99-34, 8-812-248-99-38, 8-812-243-91-63, 8-929-105-68-44
Application for ordering products here
Seminar schedule here
Meso-Xanthin F199™
A new generation injectable drug with an epigenetic focus for intensive prevention of photo- and chronoaging of the skin after 25 years.
Meso-Xanthin F199™ at the epigenetic level initiates processes aimed at repairing and maintaining the stability of the DNA nucleotide sequence under conditions of oxidative stress and aging; promotes mechanical stretching and “awakening” of fibroblasts, limiting collagen degradation, activation of productive processes, which leads to restoration of the structure of the cell matrix.
Meso-Xanthin F199™ “rejuvenates” skin cells, increases the “quality of life” of cells and their durability, provides physiological renewal of the skin, restores the antioxidant and immune potential of the skin.
Advantages:
1. A unique patented multicomponent injectable drug, the key component of which is the carotenoid Fucoxanthin, which has a powerful positive epigenetic effect on the proliferation and differentiation of progenitor precursor cells, on the DNA repair of its own stem cells damaged under oxidative stress and during the aging process.
2. “Meso-Xanthin F199™” is an effective specific (selective) EPIGENETIC regulator of gene expression that encodes the most important structural and functional proteins of skin cells
3. A reliable source of effective solutions to aesthetic problems and rehabilitation of the skin of patients with chronic dermatoses. (note, a wide range of applications for solving cosmetic problems and in the complex treatment of various chronic dermatoses. Symbiosis of cosmetology and dermatology).
4. The safety, effectiveness and reliability of Meso-Xanthin F199™ has been confirmed by numerous clinical and fundamental studies and many years of practical experience in different countries.
5. Used in women and men mainly after the age of 25 years.
Main components:
- Fucoxanthin (Fucoxanthin F-199)
- Hyaluronic Acid (molecular weight 3000 kDa, concentration 1.56%)
- growth factors (EGF; bFGF; IGF-2;);
- regulatory peptides (TRX; CG);
- vitamins (A; C; E);
- amino acids;
- nucleic acids;
- coenzymes.
MesoEye C71™
Exclusive solution to aesthetic problems in the periorbital area:
- relief of manifestations of swelling and pastiness in the periorbital area;
- improving skin color, reducing the severity of dark circles under the eyes;
- increased turgor and skin tone in the periorbital area;
- smoothing the macro- and microrelief of the skin;
- reducing the severity of paraorbital hernias.
The mechanism of action of the drug is associated with the normalization of blood and lymph circulation, which prevents the occurrence of congestion in the periorbital area:
1. Normalization of local blood and lymph circulation - reducing microvascular spasm (suppressing the activity of angiotensin-converting enzyme), restoring the normal direction and intensity of blood and lymph flow, reducing the permeability of vascular cells. In total, all this prevents the occurrence of congestion in the periorbital area - direct lymphostimulating effect, reduction of arteriolar spasm, vasoprotection
2. Protection of collagen and elastin fibers, as well as other macromolecular components of the intercellular matrix from the formation of covalent cross-links as a result of glycation. This improves the mechanical properties of the skin (firmness, elasticity), which naturally leads to a reduction in the external manifestations of swelling, improved texture, etc. - improvement in the structural and functional state of the skin, revitalization, lifting.
3. Due to the presence of an opioid peptide (Hexapeptide-17), the drug has lipolytic activity, that is, it promotes a more active breakdown of lipids in subcutaneous adipose tissue - increased physiological liposis.
Compound:
MesoEye C71™ is a bioactive patented formula consisting of PeriOrbital Peptide XP2, Hexapeptide 17 and unstabilized hyaluronic acid of bioenzymatic origin in a composition with vitamins, microelements, amino acids, nucleic acids.
MD Skin Solutions
Mesoline® rejuvenating meso-cocktail for face
An effective aesthetic medicine product designed to even out skin color.
Indications:
- Dark spots.
- Smoker's skin.
- Age-related changes (heterogeneity of skin color).
- Photoaging.
Main components:
- Ascorbic acid.
- Kojic acid.
- Phytic acid.
- Sodium pyruvate.
- White mulberry extract.
Results:
The meso cocktail whitens the skin, evens out the complexion, has a depigmenting effect, provides a rejuvenating effect, and prevents the appearance of age spots during other cosmetic procedures.
Mesoline® lifting effect
A cocktail of lifting and antioxidant ingredients to restore skin elasticity.
Indications:
- Skin without tone (loss of elasticity, ptosis).
- Face contour.
- Stretch marks.
Main components:
- DMAE.
- Coenzyme Q10.
- Silicon.
- Ferulic acid.
Results:
mesoline® PERSISTENT LIFTING stimulates the production of dermal collagen, improves the structure of collagen fibers, prevents sagging and provides a tightening effect. mesoline® PERSISTENT LIFTING eliminates stretch marks, reduces the area of damaged skin, replenishing lost collagen.
Mesoline® SKIN RADIANCE
a rejuvenating, regenerating cocktail with a pronounced moisturizing effect.
Indications:
- Prevention of aging, starting from 30 years.
- Treatment of aging and damaged skin (dryness, wrinkles, loss of tone).
results
mesoline® SKIN RADIANCE improves tone, restores the firmness, brightness and elasticity characteristic of young skin.
mesoline® SKIN RADIANCE strengthens the skin's barrier function, prevents moisture loss and maintains a high level of hydration.
mesoline® SKIN RADIANCE promotes skin cell renewal thanks to the presence of a complex of growth factors.
Main components
- Hyaluronic acid.
- Complex of growth factors.
- DNA.
- Vitamins.
- Panthenol.
Mesoline® anti-cellulite effect and increase skin elasticity
A unique selection of ingredients for cellulite correction with draining and tightening effects. Activate microcirculation and increase skin tone.
Indications:
- Cellulite (orange peel effect).
- Loss of skin elasticity due to aging and weight fluctuations.
- Swelling/heaviness in the legs.
Main components:
- L-carnitine.
- Artichoke.
- Centella Asiatica.
- Butcher's broom.
- Organic silicon.
- Caffeine.
Results: stimulates the process of lipolysis: after the first correction sessions, a pronounced decrease in the “orange peel” effect is observed, the correction area looks smoother and slimmer due to the strong emulsifying properties of phosphatidylcholine. Activates drainage and detoxification, reduces swelling. Restores skin firmness and elasticity.
Mesoline® luxury hair
Indications:
- Hair loss, hormonal or hereditary.
- Hair loss associated with stress, fatigue or pregnancy.
- Baldness associated with hair dehydration.
Main components:
- Complex of hair growth factors.
- Coenzyme Q10.
- Hyaluronic acid.
- Copper peptide.
Results:
Mesotherapy with mesoline® LUXURIOUS HAIR supplies the hair matrix with the nutritional ingredients necessary for all phases of its growth cycle, significantly reducing hair loss and improving blood microcirculation in the hair follicle area.
Aqualyx
Aqualyx is an innovative lipolytic drug that breaks down adipose tissue and allows you to get rid of cellulite. In cosmetology, Aqualyx is used for local correction of fat deposits on the abdomen, thighs and buttocks. The effect of the drug is comparable to the results of plastic surgery.
Intralipotherapy with Aqualyx
Intralipotherapy (Metolese injections) is the injection of Aqualix into the subcutaneous adipose tissue with special Lipoinject needles. The technique was developed by Italian plastic surgeon Pascual Motolese. Needles for intralipotherapy are made of steel; cosmetologists use 70 and 100 mm needles.
The drug Aqualyx acts on the membranes of fat cells, dissolving them, and stimulates the functioning of the lymphatic system. After a course of injections, cell breakdown products are eliminated from the body naturally.
Benefits of body contouring with Aqualyx
- Local effect of the drug. Therapy with Aqualix is ineffective in the treatment of general obesity. The drug acts precisely, breaking down adipose tissue and normalizing metabolic processes;
- To get rid of cellulite, one or two injections are enough;
- Aqualix is safe for health (confirmed by certificates);
- The active substance of the drug - modified sodium salt of deoxycholic acid - acts within 3-5 minutes. This time is enough to dissolve fat cells;
- Aqualyx effectively eliminates fat deposits on the thighs, buttocks, sides, abdomen and inner arms. The drug can be used by both women and men. After intralipotherapy with Aqualix, the skin maintains an even contour.
Aqualyx injections enhance the effect of pressotherapy and anti-cellulite massage.
BIO-R is a new generation biorevitalizant
Long-acting biorevitalizant based on high-molecular hyaluronic acid of non-animal origin.
Advantages of the drug: Effective - Gives visible and lasting results.
Safe: Available in sterile syringes for single use, registered (certified) and approved for use in the Russian Federation. The studies carried out did not reveal any side effects or reactions. Replenishes hyaluronic acid deficiency and normalizes cellular metabolism. Over time, it completely biodegrades, leaving no decay products at the injection site.
Indications for use:
- Wrinkles in the perioral and periorbital area
- Dry and dehydrated skin
- Dermal folds
- Thick, atonic skin
- Decreased elasticity and skin tone
- Flabbiness of facial skin
- Atrophic scars, including acne scars
- Flabbiness of the skin of the abdomen and thighs
- Striae
The most popular beauty treatments: masks
The difference between masks and regular creams is that they penetrate deep into the skin, thereby having a greater effect on the skin of the face. This is one of the reasons why they are used less often than creams. Masks do not affect the skin as deeply as other procedures, but they provide the top layer of skin with complete nutrition and hydration. Here are the masks that can be made in most salons:
- Moisturizing and nourishing for dry and combination skin, especially in winter. In some cases, they are indicated for oily and normal skin - a cosmetologist will tell you more precisely, since everything is individual. In general, nutritional hydration is necessary for everyone, regardless of skin type;
- Enzyme masks for aging and aging skin. Enzymes improve the process of cell division, thereby promoting rejuvenation and renewal. The effects of such masks are quite serious, so they are not recommended to be used frequently;
- Alginate masks are an excellent end to a massage. It is a powder that is diluted in liquid and applied to the skin. All nutrients penetrate very deeply into the layers of the skin, due to blocking the access of oxygen for a short period of time;
- Seaweed is a great way to lighten your skin. If such a mask is applied to the neck and décolleté, it will benefit the thyroid gland (there is a lot of iodine in the composition). There is a minor drawback - masks can have a very unpleasant specific smell;
- Toning masks help stimulate blood circulation and improve blood flow. The skin thereby regains its tone and radiance, which is very important during the hot season.
Hyalual
Injectable preparation for the redermalization procedure.
A unique formula combining sodium succinate and hyaluronic acid:
Sodium succinate provides a powerful restorative effect, stimulates the synthesis of collagen and elastin, enhances microcirculation, and has an antioxidant effect.
Hyaluronic acid – eliminates skin dehydration and moisturizes it.
Redermalization is skin rejuvenation by restoring its dermal layer. This technique affects all three main pathogenetic mechanisms of skin aging:
- Regulates biochemical and physiological processes in cells.
- Actively blocks free radicals.
- Eliminates skin dehydration
The result is a comprehensive anti-age effect:
- Skin restoration - improving its texture and appearance, increasing firmness and elasticity, eliminating hyperpigmentation
- Skin rejuvenation – powerful lifting, wrinkle reconstruction
- Improved skin nutrition - improved complexion
- Slowing down aging – preventing cell destruction and the formation of atypical cells
Range of drugs recommended for cosmetologists
The range of Medicare products includes all the drugs necessary to maintain health: moisturizers, cleansers and rejuvenators, for problem skin. This allows cosmetologists to significantly improve the quality of services offered, guaranteeing their clients excellent results in the next two weeks. You should not expect the effect on the day of using cosmeceuticals, since its effect can be noticed after a certain period of time, when changes occur at the cellular level.
Skin requires regular comprehensive care. If peeling can be carried out on the recommendation of a specialist and not on a regular basis, then with age the use of anti-aging products is mandatory. The body stops coping with assigned tasks, metabolic processes decrease, and skin cells suffer from a lack of oxygen and other nutrients. Medicare has developed a unique formula that allows you to intensively rejuvenate your skin. During care, important attention is paid to cleansing the skin. Cleansing is required regularly to ensure normal physiological processes and improve the penetration of the active ingredients included in the drug into the cells.
When choosing a suitable skin care product, any cosmetologist must have special preparations for correcting problem skin. Now Medicare has offered cosmeceuticals that can restore skin, narrow enlarged pores, eliminate comedones, and even out skin texture and color.
Meso-Wharton P199™
Meso-Wharton P199™ is the perfect bioreparant and restructuring agent for the 21st century.
An injectable preparation for medical purposes, intended for intensive repair and “rejuvenation” of facial skin after 40 years.
An innovative drug with proven high efficiency, safety and an impeccable reputation, Meso-Wharton P199™ initiates deep, lasting anti-aging and regenerative processes in the skin, which are the result of activating the proliferation and differentiation of the skin’s own stem cells, replacing sluggishly renewed cellular structures of the epidermis and dermis, increasing synthetic fibroblast activity, stimulation of the formation of new collagen.
The Meso-Wharton P199™ injectable drug opens up new possibilities for anti-age therapy - the dream of youth has come true.
Main components:
- "Wharton Jelly Peptide P199"
- hyaluronic acid with a molecular weight of 3300 kDa – 1.5%;
- growth factors (EGF; bFGF; IGF-2);
- thioredoxin (TRX);
- vitamins (A, group B, C, E, K, folic acid);
- amino acids;
- nucleic acids;
- microelements;
- coenzymes.