Intraject Hyaluform 1.8% (synovial) is a colorless, transparent, viscous, pyrogen-free gel that is supplied in a glass syringe. This is a unique form of highly purified hyaluronic acid obtained through bacterial fermentation. The material does not contain animal proteins and does not require preliminary allergy testing. Hyaluronic acid is a natural glycosaminoglycan of the intercellular matrix, which has the greatest hygroscopicity of all known natural mucopolysaccharides.
Description of the drug
Hyaluform is produced in the Toscani Laboratory, owned by the Russian company Martinex. To produce the line of drugs, hyaluronic acid is used, which is synthesized by Japanese scientists from the Shiseido laboratory. All products have appropriate quality certificates. Both the Martinex company and the laboratory itself have official websites, where you can get detailed information about the drugs.
Compound
Hyaluronic acid is an important component of human skin and a popular component of anti-aging products. It moisturizes the dermis, increases its elasticity and tone, promotes regeneration, and improves blood circulation. Hyaluronic acid is the basis of all Hyaluform preparations. They are available in different volumes and concentrations.
Attention! You should not overuse hyaluronic acid, otherwise the skin will stop producing it on its own.
Indications for use and effectiveness
The drug has a wide spectrum of action. It is often used for facial rejuvenation, oval correction, wrinkle smoothing, and in preparation for plastic surgery and cosmetic procedures. In addition, various forms of Hyaluform can cope with the following problems:
- dryness, sagging skin of the face, neck, décolleté;
- rosacea (capillary mesh);
- stretch marks on the body;
- scarring;
- disturbed water balance of the dermis, etc.
With the help of Hyaluform, it will be possible to add volume to the lips, remove medium and deep folds, wrinkles, perform modeling of the shape of the nose and ears, “prosthetics” of joints, as well as intimate contouring. There is no single drug in the line that would simultaneously solve all these problems. Each variety of Hyaluform has its own purpose.
Depending on the problems that need to be solved with injections, hyaluform can be used from the age of 18. However, the drugs are not universal. Some of them are intended for women who are over 25 years old, while other products are suitable only for ladies who have crossed the 45-year mark.
Kinds
The products differ in indications for use, release form, and concentration (for example, Hyaluform 1.8% or 2.5%). The higher this indicator, the more complex problems the drug can solve. Low-concentrated hyaluronic acid (1% or 10 mg/ml) is designed to eliminate fine wrinkles and the first signs of skin aging, therefore it is usually used for women aged 25 years and older. Hyaluform 2.5% is a more powerful product designed to smooth out deep folds and rejuvenate the skin.
The manufacturer Martinex produces the following forms of the drug:
- Fillers for contouring, bioreinforcement (strengthening the dermis and increasing its elasticity), eliminating wrinkles. This line includes Hyaluform Normal (Normal) 1.8%, Deep (Deep) 2.5% and SubDerm 2.5%. The peculiarity of the Subderm filler is that it has a prolonged effect. Previously, the company produced filler LIGHT with a concentration of 1%, but now there is no information about it on the official website, and the drug itself is not available in distributors’ warehouses.
- Biorevitalizants for smoothing deep wrinkles, restoring the water balance of the skin, correcting the oval of the face. There are products in concentrations of 1% and 1.8%.
- Hyaluform mesolift to moisturize the skin, increase its tone and improve elasticity. Available in bottles of 2.0 and 2.5 ml. There are concentrations of 1%, 1.8% and 2.5%. The first drug can be used independently, the other two can only be used in mesotherapy cocktails.
- Intraject Hyaluform (synovial) 1% and 1.8% is a liquid implant for intra-articular administration. It relieves pain and replenishes the deficiency of synovial fluid, which is responsible for shock absorption of the joint. In addition to injection, Intraject is available in gel form.
Important point! It is impossible to say unequivocally which Hyaluform is better. Each form of the drug is aimed at solving a specific range of problems. Choose what is designed to solve your particular problem.
Price
If you want to be 100% sure that you are purchasing quality products, cooperate with Martinex representatives. In addition to Russia, they are in Ukraine, Georgia and other states of the post-Soviet space. Addresses and telephone numbers of distributors can be found on the company's official website.
Hyaluform is also sold in online stores. Choose online outlets that have good reviews from customers. The cost of fillers is about 5-7 thousand rubles, biorevitalizants - 3-4 thousand rubles per bottle. Mesolifts have the lowest price - from 1000 to 1500 rubles.
Hyaluform 1% 2ml Synovial
Additional information: Drug type medicinal product
Pharmacological group of medical devices
Prescription drug yes
Release form solution for intra-articular administration
Volume 2
Area of application for joint diseases
Pharmacological action restores the physiological and rheological properties of the synovial fluid of a joint affected by osteoarthritis, reduces pain and discomfort, improves mobility in the joint
Indications for use : temporary replacement and replenishment of synovial fluid; primary and post-traumatic osteoarthritis of synovial joints; moderate and moderate severity of osteoarthritis; simultaneous treatment of several joints is possible
Ingredients : unstabilized hyaluronic acid (sodium salt) 10 mg/ml; water for injection, pH 5-7 sufficient quantity
The interaction between the effectiveness and safety of the drug in combination with simultaneous intra-articular administration of medical devices has not been studied, therefore the combined use of the drug with other medical devices is not recommended; incompatibility has been noted between sodium hyaluronate and quaternary ammonium salts, such as benzalkonium chloride
Contraindications: hypersensitivity or allergy to components; a history of autoimmune diseases or autoimmune therapy; pathological bleeding (endogenous or caused by the use of anticoagulants); infectious (septic) inflammatory process in the joint or periarticular tissues, intra-articular effusion, general infectious disease; presence of signs of active skin disease or skin infection in the immediate vicinity of the injection site; pregnancy and lactation; children under 18 years old
Dosage: Carefully treat the injection areas with an antiseptic and allow the skin to dry; synovial is intended for intra-articular injection, the mode of administration depends on the severity of degenerative or traumatic changes in the joint and is determined by the attending physician; The recommended course of treatment with the drug for patients with moderate to moderate severity of osteoarthritis is 3-5 injections of 2.0 ml (needles - from 19 to 21 g) into the synovial space of the joint with a week interval between each; the maximum recommended course duration is 6 weeks; if necessary, repeated courses of treatment may be prescribed; a repeat course is carried out no earlier than after 6-12 months; simultaneous treatment of several joints is possible; treatment with the drug affects only the affected joint into which the material is injected; it does not have a systemic effect; administration of the drug can only be performed by a doctor with special training, in a medical institution, in a room equipped for intra-articular administration of drugs, in compliance with all rules of asepsis
Use during pregnancy is contraindicated
Side effects: intra-articular administration of the drug is well tolerated; in rare cases, local secondary phenomena are possible: pain, sensation of warmth, redness, swelling of the joint, the appearance of intra-articular exudation, extremely rarely allergic reactions; side effects may appear immediately or after some time; the phenomena are short-lived and disappear spontaneously; in exceptional cases, septic arthritis may occur, including that not associated with the use of the drug; symptoms: the appearance of a local inflammatory reaction, increased pain in the joint, increased body temperature
Storage conditions: Store in a place protected from sunlight at a temperature of +5 to +25 ° C; do not freeze
Special instructions should be observed to comply with sanitary and epidemiological requirements when performing intra-articular injections, as there is a possible risk of infection; intravascular administration of the drug is unacceptable; avoid getting material into the joint capsule, surrounding tissue or blood vessels
Filler injection
First of all, you need to choose a competent specialist who will advise you on all issues, tell you which drug from the Hyaluform line is suitable in your case and how many procedures will be required. A good cosmetologist is obliged to warn the patient about possible side effects and consequences, and tell them about proper facial care after injections. And most importantly, he must perform the procedure efficiently.
Don’t risk your health and beauty: trust the injection of hyaluronic acid exclusively to professionals.
Give preference to a salon that has the right to provide therapeutic and surgical cosmetology services. To make sure of this, ask to see the relevant license (often posted publicly). The choice of doctor is no less important. A qualified specialist must have certificates confirming his right to work with drugs, including Hyaluform.
Description of the procedure
Before the beautician begins to inject, make sure that he is going to use a new bottle or ampoule that has not expired.
A tightly closed container with partially used hyaluronic acid is stored for some time in the refrigerator (from several hours to 1-2 months), but only if sterility is maintained during opening. Ampoule preparations have a shorter shelf life than products from a bottle.
Details are usually provided in the instructions. An experienced specialist will not take risks and will take a new product.
The filler injection process itself looks like this:
- The doctor cleans the patient’s face of makeup and dirt.
- Uses an anesthetic - lidocaine or something else.
- After the anesthetic takes effect, the cosmetologist treats the face or other affected area with an antiseptic. For example, chlorhexidine.
- The specialist opens the package so that the patient can see it. If necessary, takes the substance from the bottle, mixes it with other components or dilutes it. Hyaluform fillers are produced in branded syringes and are immediately ready for use.
- The doctor administers the substance to the patient. If a biorevitalizant is used, prepare for small targeted injections, during which discomfort is possible. For fillers, a linear technique is often chosen, injecting strips of gel under the wrinkles.
- The procedure lasts from 30 minutes to 1 hour - it depends on the size of the area being treated and the complexity of the work. If in addition to the face you need to treat the neck or décolleté area, the procedure time increases.
- The cosmetologist performs a special massage to evenly distribute Hyaluform over the skin.
Healing period and care
At the injection sites, bruises and swelling may form on the patient’s face, which last up to 1 week. Much earlier - about 2 days after the procedure - papules (gel compactions similar to balls) should disappear. They cannot be massaged on their own, so as not to infect the wounds left after Hyaluform injections. For some, papules may smooth out within a couple of hours after administration of the drug, but if they persist for more than a day, this is a reason to consult a doctor.
For the first few days, you need to protect your skin from heat exposure: sunlight, baths, solarium, as well as heat emitted by a stove or open fire (fireplace, bonfire). Intense massage and diligent rubbing of any products (medicines, cosmetics) into the skin are prohibited. You cannot use foundation or powder or go to the pool.
Attention! On average, the effect of Hyaluform fillers lasts for 3–6 months. After a certain interval, the cosmetologist may recommend additional procedures to consolidate the result.
Price
Traditionally, Moscow prices are the highest. In a metropolitan salon or clinic, you will have to pay from 9 to 19 thousand rubles for 1 procedure using Hyaluform. The cost depends on the type of drug and the qualifications of the specialist. In the regions the service is cheaper.
What is Hyaluform
The developer of Hyaluform is Martinex, which is undoubtedly a leader in the field of aesthetic medicine and cosmetology on the Russian market. The raw materials for creating the gel are purchased from the Japanese company Shiseido. Hyaluronate, which is part of Hyaluform preparations, undergoes a three-phase stabilization method, which is fundamentally different from other products.
Hyaluform is used for injection cosmetology, that is, the drug is injected under the skin. This method allows you to stimulate internal processes, including increased regeneration and hydration of epidermal cells. Modified hyaluronic acid molecules help prolong the effect after correction and contouring.
Composition and features
Hyaluform products are designed to eliminate aesthetic defects. Bioactivating mesotherapy has quick and long-lasting results. The drug can be used in medical clinics. Designed to saturate the skin with moisture and restore water balance. Mesolift is used as part of many cosmetic cocktails, in combination with silicone, structucoll, vitamin C, caviar and other synthetic substances.
Hyaluform biorevitalizant is used for biorevitalization. Perfectly fills small wrinkles, improves skin structure, and has a lifting effect. It is often used before plastic surgery and peeling.
Hyaluform filler helps smooth out deep skin creases, saturate the epidermis with moisture, and eliminate excessive dryness. It is used in shaping the contour of certain areas of the face.
Indications for use
Hyaluform is not only different from all similar products, it is one of a kind. The line of drugs is produced in three forms: biorevitalizer, filler, mesolift. Each has its own tasks and goals, facilitated by different composition and concentration.
Biotechnological hyaluronic acid, part of Hyaluform, is a synthetic substance and heals the epidermis at the cellular level.
Hyaluform Mesolift 1%, 1.8% and 2.5%
It contains unmodified biotechnologically produced hyaluronate. The choice of product concentration is determined by the volume of the treated area. Used to get rid of free radicals, moisturize the skin and reconstruct the intercellular structure.
Indications:
- dehydrated skin;
- crow's feet and bags under the eyes;
- preparation or restoration of the epidermis during UV trauma;
- rosacea;
- atrophic scars;
- before and after laser facial resurfacing, plastic surgery and acid peels.
Used alone or as a base for cocktails, the area of influence is increased thanks to other components.
Additional components:
- 0.5 and 1% Silicin - moisturizing the face, hair, body and defibrosant;
- DMAE – lifting;
- Caviar, Struktukoll, REGENERADOR FACIAL A-36 – complete restoration of the structure of the dermis;
- vitamin C - antioxidant protection.
Hyaluform Biorevitalizant 1%
The drug contains biotechnological unstabilized hyaluronic acid.
Indications:
- thin skin that has lost its tone;
- dry skin;
- uneven complexion;
- prevention and correction of photodamage to the epidermis;
- shallow wrinkles;
- preparation for injections biorevitalizant 1.8%;
- before performing chemical peels, laser rejuvenation and plastic surgery.
The biorevitalization product has a strong moisturizing and restructuring effect, retains the required amount of moisture in the skin and creates an ideal environment for further independent restoration of the dermis.
Cosmetologists use several techniques for introducing biorevitalizant: tubercular, papular and linear.
Hyaluform biorevitalizant 1.8%
The active component of the drug is biotechnological hyaluronic acid, stabilized by the solid-phase method.
Indications:
- thick, lacking tone skin;
- creases and deep wrinkles;
- normal, oily skin;
- need for lifting;
- stretch marks, atrophic scars, post-acne;
- after using biorevitalizant 1% to prolong the hydration of the dermis.
Biorevitalizant 1.8% has a powerful lifting effect in combination with long-lasting hydration. Since the product is partially stabilized, it remains in the dermis for a long time. And due to its viscosity, it is excellent for bio-reinforcing the skin.
Recommended insertion techniques are linear and cusp.
Hyaluform filler Normal 1.8%
The normal filler contains 1.8% hyaluronate.
Indications:
- earlobe modeling;
- correction of facial and age wrinkles;
- reconstruction of the shape and volume of the lips;
- atrophic scars, stretch marks, post-acne;
- skin reinforcement.
Other areas of application for all fillers include the hands, the anterior abdominal wall, the inner surface of the shoulder and thigh, and elbows.
Administration techniques used by clients: bolus, linear, fan.
Hyaluform filler Deep 1.8%
The active component of the drug is 1.8% hyaluronic acid.
Indications:
- smoothing deep folds and wrinkles;
- atrophic scars, stretch marks, post-acne;
- restoration of lip volume and shape;
- return of the lost volume of soft tissues of various zones (zygomatic, buccal, frontal, temporal);
- non-surgical change in the shape and size of the nose and earlobes;
- intimate filling.
Hyaluform filler SubDerm 2.5%
The drug Sabderma is the first Russian volumizer. Contains hyaluronic acid 2.5%. Indications and action are very similar to Deep filler 1.8%, only due to increased concentration, it has a longer effect.
Synovial hyaluform 1%
The drug is a liquid implant created for intra-articular administration via a needle. Hyaluronic acid improves the gliding of joint surfaces in the patient, providing shock absorption. Synovial also helps relieve pain, clear dead cells from the injured joint and stimulate the production of its own hyaluronate.
How to remove the drug
If you don’t like the result of the procedure, you will have to contact your doctor with a request to dissolve the filler. This can be done already in the first two days after the injections. The doctor will inject the patient with a special enzyme that will partially or completely remove hyaluronic acid from the body. However, experts advise not to rush.
In the first days after using Hyaluform, the face will not fully look the way it should: the drug is still absorbed under the skin. The final result can be assessed 7–10 days after the injections. If it still turns out to be unsatisfactory, visit the cosmetologist again.
Precautionary measures
In addition to papules, hematomas and edema, the patient may encounter the following unpleasant consequences at the injection sites of Hyaluform:
- itching, pain;
- proliferation of connective tissue, appearance of nodules;
- allergic reactions;
- change in skin color.
All this is partly due to the individual characteristics of the body, as well as the quality of the drug and the sterility of the procedure. In addition, in order to minimize the risk of side effects and complications, a number of contraindications must be taken into account. You should not inject Hyaluform if you:
- you suffer from an acute infectious disease;
- have problems with blood clotting (due to medications or illness);
- are expecting or breastfeeding a baby;
- are sick with oncology;
- you suffer from intolerance to drugs based on hyaluronic acid.
Also, Hyaluform injections are prohibited if there is inflammation on the skin or if lumps are felt after the previous injection of fillers (any). Fungal, bacterial, viral infections of the skin, as well as autoimmune diseases and the presence of keloid scars - all these factors also make the procedure impossible.
Important! An allergic reaction may occur not to Hyaluform itself, but to other drugs, for example, an anesthetic. Be sure to tell your doctor if you have intolerance to any medications.
Contraindications and side effects
Hyaluform is not recommended for use in certain diseases and conditions:
- infectious and inflammatory lesions in the area of the intended injection;
- period of pregnancy and lactation;
- allergic reaction to the components of the drug;
- exacerbation of chronic diseases;
- the presence of hypertrophic or keloid scars;
- severe somatic illnesses.
A person may experience some side effects after injections, most often these are pain, itching and burning, bruising and nodules at the injection site. Symptoms usually go away without treatment within a week.
Advantages and disadvantages
The domestic product differs from imported fillers in plasticity and concentration, as well as price. For example, Restylane fillers can cost 9.5 thousand rubles, and Juvederm - 11–12,000 rubles. In addition to cost, Hyaluform has the following advantages:
- moisturizes, heals and rejuvenates the skin;
- smoothes wrinkles;
- improves complexion and shape of the face;
- allows you to correct other parts of the body - lips, nose, etc.;
- gives quick results.
The disadvantages of Hyaluform include:
- presence of side effects;
- risk of developing allergies;
- possible discomfort during the procedure;
- the need to comply with storage conditions and rules for administering the drug.
Instructions for use
Intraject injections are intended for injection into the joint cavity . The solution should not get into the joint capsule, nearby tissues or bloodstream.
Important! The procedure is carried out only by a doctor with appropriate training in an equipped room under conditions of absolute sterility.
Before the injection, the specialist performs the following steps::
- Warms the drug to room temperature, for which it is removed from the refrigerator 20 minutes before use.
- Treats the injection area with an antiseptic.
- If there is pathologically accumulated fluid, remove it before administering the drug.
- Gives an injection.
The standard course of therapy for moderate and intermediate stages of pathology development includes 3-5 injections , which are given once a week.
Reference . The maximum duration of treatment is 6 weeks.
If necessary, repeat courses are prescribed . Repeat therapy is allowed no earlier than six months to a year. Simultaneous treatment of several affected joints is possible.
During pregnancy and lactation
Information on the safety of using the drug during pregnancy and breastfeeding is not provided . The drug can be used only by the decision of the attending physician.
For children and the elderly
Contraindicated for the treatment of children and adolescents under the age of 18 , since there is no information on the safety and effectiveness of using the drug in pediatrics.
Features of the use of the drug in old age have not been established.
Opinion of cosmetologists
Hyaluform is not a new product - many cosmetologists have been successfully practicing it for several years. During this time, doctors managed to evaluate the ease of use and effectiveness of the drug, as well as its price.
The author of this review compares Hyaluform with the drug IAL-system and gives preference to the first. Since the active substance in both cases is the same - hyaluronic acid - the cosmetologist finds other advantages of Martinex fillers.
For some specialists, the cost of the drug is the main advantage.
Several years ago, cases of allergic reactions in patients became more frequent. This is what the cosmetologist who practiced the introduction of Hyaluform says.
During this period, some experts noted the difficulty of working with the drug.
It turned out that the problems were related to the consistency and composition of Hyaluform.
Even after the issue was resolved, some cosmetologists began to be wary of the drug.
Compound
"Intraject" is a drug in the form of an artificial liquid . It has a similar composition and properties to synovial fluid (synovium), which fills the joint cavity. The drug is prescribed to replace or eliminate the lack of intra-articular fluid during the treatment of lesions of the musculoskeletal system (MSA).
The drug contains one active component - unstabilized hyaluronic acid . It is obtained using bacterial fermentation (biochemical processing of raw materials). There are no animal proteins in the solution, so there is no need to conduct a preliminary allergy test.
Reference . Hyaluronic acid is a substance produced in the body. Part of connective, epithelial and nervous tissues. Refers to the important components of synovium, responsible for its physiological properties.
Excipient – injection water.
Patient reviews
Women who have undergone the procedure using Hyaluform also express mixed opinions. The author of this review was delighted with the effect obtained, which she maintains with repeated injections.
There are also sharply negative assessments of the drug, which are mostly associated with side effects and the development of allergic reactions.
How the skin will react is difficult to predict, but this gives patients reason to doubt the quality of the products.
This woman liked the results of the procedure, but did not find it to last too long.
The patient advises to carefully choose the specialist who will perform the injections, so that later you also do not have to write a negative review.
Women who have used Hyaluform praise it for its quick and noticeable results. At the same time, there are indeed many reviews that the drug often causes allergies, swelling, and papules do not resolve for a long time. If negative opinions do not stop you, study the reputation of different cosmetology clinics and salons, choose an experienced and qualified doctor.
Prepare well and do not go for injections if there are contraindications. Discuss all the details of the procedure with your doctor to make a final decision and reduce all possible risks when performing injections.
Mode of application
Before administering Intraject hyaluform 1.8% (synovial), it is necessary to thoroughly treat the injection areas with an appropriate antiseptic and allow the skin to dry.
The drug is intended for intra-articular injection; the mode of administration depends on the severity of degenerative or traumatic changes in the joint and is determined by the attending physician. Administration into the intravascular or extra-articular space, as well as into the tissue of the synovium or joint capsule is unacceptable.
It must first be warmed to room temperature, and therefore the syringe should be removed from the refrigerator at least 20 minutes in advance. before use.
The recommended course of treatment with Intraject hyaluform 1.8% (synovial) for patients with moderate to moderate severity of osteoarthritis is 3-5 injections of 2.0 ml (needles - from 19 to 21 G) into the synovial space of the joint with a week interval between each . The maximum recommended course duration is 6 weeks. If necessary, repeated courses of treatment may be prescribed after 6-12 months. It is possible to treat several joints simultaneously.
