Composition and release form
Radevit is produced in the form of an ointment for external use in tubes of various sizes.
It contains fat-soluble vitamins (active components) and excipients. Main active vitamins:
- A – has an anti-inflammatory effect, restores the epidermis.
- D3 – has an anti-inflammatory effect, antioxidant.
- E – has a rejuvenating effect, antioxidant.
Auxiliary components:
- glycerol;
- ethanol;
- butylated hydroxyanisole;
- butylated hydroxytoluene;
- emulsion wax;
- Vaseline oil;
- purified water.
The form of vitamin A in the cream is retinol palmitate. Its effectiveness is significantly lower than that of pure retinol. But thanks to retinol palmitate, as well as petroleum jelly and glycerin, skin regeneration and hydration occurs.
Does Radevit ointment help against wrinkles: reviews
Very often, customers get confused and ask pharmacies not for ointment, but for Radevit cream (this form of release does not exist). You can buy Radevit ointment in almost every pharmacy.
For Radevit ointment, the price will be only about 340-380 rubles (per tube of 35 g).
Radevit Active is produced in the form of an ointment containing fat-soluble vitamins A, D, E - in tubes of 10, 20, 35 g.
Active substances in 1 g of ointment –
- vitamin A (retinol palmitate) – 10 mg,
- vitamin D3 (colecaciferol) – 50 mg,
- vitamin E (alpha-tocopherol acetate) – 5 mg.
Excipients: butylated hydroxyanisole – 1 mg, butylated hydroxytoluene – 1 mg, emulsion wax – 80 mg, petroleum jelly – 50 mg, glycerin – 100 mg, ethyl alcohol 95% – 100 mg, purified water – up to 1 g.
Analysis of the composition - vitamin A is the only component here that can prevent photoaging of the skin, or even achieve a slight reduction in the depth of wrinkles. It must be said that vitamin A in Radevit is presented in the form of retinol palmitate, which is not pure true retinol, but only an ester of retinol.
When penetrating the skin, retinol palmitate will slowly transform first into pure retinol, then into retinaldehyde, and then into retinoic acid, which is the only effective form of vitamin A. It must be said that only retinoic acid (of all forms of vitamin A) - Skin cells have special receptors. And that any form of vitamin A must first be transformed into retinoic acid before it can act on the skin.
However, as a result of this conversion process, retinol palmitate loses up to 90% of its activity and effectiveness, and only a little pure retinol is formed from it, and even less retinoic acid.
Important: the concentration of vitamin A in Radevit ointment is 1%. For example, the recommended concentrations of true retinol in anti-wrinkle medicinal cosmetics should be from 0.5 to 1%. Most of the retinol palmitate when converted to pure retinol will be destroyed during the transformation process. This means that in order for retinol palmitate to have an effect comparable to the effect of 1% pure retinol, its concentration must be several orders of magnitude higher.
Another disadvantage of retinol palmitate compared to other forms of vitamin A (such as retinoic acid or pure retinol) is that retinol palmitate penetrates the skin to a shallower depth, affecting mainly only the epidermis. Those. it practically does not penetrate into the dermis, where fibroblasts that produce collagen and elastin are concentrated.
The advantages of Radevit ointment - thus, retinol palmitate will work perfectly only in the epidermis, promoting the regeneration of its cells, its hydration, and also increasing the hydrophobic properties of the skin. The remaining vitamins included in Radevit are also able to act only on the surface layer of the skin, as they cannot penetrate deeper.
But, despite this, Radevit heals dry and irritated skin very well, and can act as an excellent protective cream for dry skin, improving its protective properties under adverse environmental conditions.
Many patients tried to use Radevit anti-wrinkle ointment - reviews from such patients showed its ineffectiveness in the fight against fine wrinkles on the face. Even after six months of daily use of this product, patient reviews reported that there was no significant reduction in wrinkles and fine lines on the face.
Although these same reviews note that after regular long-term use, dry skin became softer and less irritated, less likely to dry out and flake, and looked healthier. Therefore, we recommend using Radevit only to prevent photoaging of the skin, but not to reduce existing wrinkles or fine lines on the face.
The form of vitamin A (retinol palmitate) included in Radevit ointment cannot penetrate into the deep layers of the skin and effectively interact with fibroblasts that produce collagen and elastin. Let us remember that only acidic forms of vitamin A, which include Tretinoin and Isotretinoin, are better than other forms of vitamin A in being able to penetrate into the deepest layers of the dermis, stimulating the production of collagen and elastin by fibroblasts there.
It is these forms of vitamin A (belonging to the group of topical retinoids) that can reduce the depth of wrinkles, which is confirmed by clinical studies. Drugs based on Tretinoin and Isotretinoin include:
→ “Retin-A” cream (Fig. 4), → “Retinoic ointment” drug (Fig. 5).
There are other forms of vitamin A that will be weaker than Tretinoin and Isotretinoin, but much stronger than retinol palmitate. We are talking about anti-aging cosmetics with pure retinol or retinaldehyde (Fig. 6). Their advantage is that they will cause less dryness and redness of the skin than retinoic acid-based products.
Therapeutic masks with “Radevit” for moisturizing and wrinkles
Aging of the body is inevitable. But external signs of age-related changes - sagging skin, wrinkles, drooping facial contours, uneven skin color - can be significantly reduced with the help of various cosmetic procedures.
There are a lot of means to preserve a youthful face. But women always try to find the ideal product that combines effectiveness and affordability.
It’s no secret that some anti-aging cosmetics are quite expensive, and the effect of their use is not immediately visible.
Therefore, in search of inexpensive and effective remedies for wrinkles, women turn to the pharmacy for various ointments. Such an ointment is Radevit, which is used for wrinkles.
Radevit face cream is often used as part of homemade masks. Depending on the components, you can prepare nourishing, moisturizing, anti-aging masks.
To combat wrinkles and moisturize the skin, use the following mask:
- Brew chamomile according to the instructions on the package and let it brew.
- Add a little oatmeal or clay to ¼ cup of broth. Mix.
- Add a 2 cm strip of Radevit. Stir thoroughly and apply to face. Leave for 20 minutes, then remove any remaining mask.
To moisturize the skin, you can also use this mask option:
- Prepare calendula infusion.
- Mix ¼ cup with a small amount of starch.
- Add a strip of Radevit 2 cm.
- Mix everything. Apply in a thin layer.
- After 20 minutes, remove everything.
Consumer Reviews
Numerous reviews that come from people who have tried the effects of Radevit on themselves cannot go unnoticed. Women praise this miraculous cream in every possible way, which, according to them, made the skin firm, soft and elastic.
The consistency of Radevit resembles a regular cream of medium thickness, which does not contain fragrances. The rapid absorption of the drug allows you to apply it to the skin immediately before bed. During the daytime, the majority of women used the ointment as a base for makeup. Thanks to this solution, the skin will be protected from exposure to direct sunlight, and a layer of decorative cosmetics will protect Radevit from ultraviolet radiation.
But still, the majority of consumers replaced their everyday cosmetics with cream. If we talk about the real result, the young ladies got rid of problems such as pimples, blackheads and skin redness. 3 weeks after the first use, the skin became smooth without traces of acne. Women after thirty years got rid of dry skin, facial wrinkles, and the deep “furrows” on the skin were significantly smoothed out. The first results from using Radevit are noticeable after 4 days.
Radevit anti-wrinkle ointment perfectly moisturizes not only the skin, but also the lips. In this case, women were convinced of this in winter, when the risk of chapped lips increases. Radevit serves as protection and replaces hygienic lipstick. Some people used the drug as a moisturizer for the elbows and feet.
Those with sensitive skin felt the gentle effects of the drug. They noted that irritation and peeling disappeared, and no side effects occurred. In addition, the effectiveness of Radevit is also proven by medical specialists. The ointment is prescribed to patients for minor skin problems: peeling, irritation, rashes and dryness.
Thus, Radevit is a universal remedy that helps get rid of not only age-related skin changes, but also many problems associated with it.
pharmachologic effect
The effect of Radevit cream is due to its active ingredients. Vitamin A regenerates cells, restores skin elasticity, reduces wrinkles, prevents photoaging, improves skin color, makes it more beautiful and hydrated. Vitamin D relieves inflammation and strengthens local immunity. Vitamin E is a powerful antioxidant, protects the skin from free radicals, and moisturizes.
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Contraindications
Due to its vitamin composition, Radevit cream for the face, lips, and hands is often used by girls and women.
However, it has medicinal properties and is used in complex therapy for the following skin diseases:
- allergic reactions;
- eczema, psoriasis;
- neurodermatitis;
- various types of dermatitis;
- burns;
- skin ulcers;
- ichthyosis;
- dry skin;
- wounds and cracks.
Radevit cream should not be used on the face, hands or for skin diseases in the following cases:
- Before using the cream, you should be tested for the amount of vitamins A, D and E in the body. An excess of vitamins can cause a backlash and cause allergies.
- Taking medications containing vitamins A, D, E.
- Pregnancy and lactation period.
- Skin diseases during exacerbation.
- Allergy to any of the components of the cream.
If hyperpigmentation or allergies occur during the use of Radevit, the cream should be discontinued.
Radevit. Contraindications
Radevit cream and ointments are contraindicated in the following cases:
- It is forbidden to use by pregnant and lactating women.
- Individual intolerance and hypersensitivity to substances in the composition.
- Inflammation of the dermis, accompanied by complications.
- Excess retinol, vitamin E or D.
If you do not follow the instructions for use, if you are allergic to the composition or use the cream or ointment incorrectly, side effects may occur:
- An allergic reaction – itching, burning, rash, redness, dryness and flaking.
- Pimples, acne.
- The appearance of pigment on the skin. It is formed if Radevit is applied directly to the skin before going out into the sun. In this case, it is recommended to apply sunscreen before going outside.
No cases of overdose were observed. It is possible only with hypervitaminosis of vitamins A, E, D.
It is not recommended to use the cream with medications that contain vitamins to avoid intoxication.
If corticosteroids are used in parallel with Radevit cream, the effect of the cream is reduced. To avoid side effects, it is recommended to use analgesics with hormonal drugs.
Radevit can be used by children in case of dry skin.
You should not choose Radevit as a treatment on your own, and it is also not recommended to choose its analogues without consulting your doctor. Before using any medicine, you must first undergo tests, and then select a medicine that is suitable for the individual patient.
Instructions for use
Radevit has a wide spectrum of action. When using it, you need to understand what effect a person intends to get. The application plan will depend on this. Radevit face cream is often used to reduce and prevent wrinkles.
Key points about using Radevit for wrinkles:
- apply twice a day: after waking up and before bedtime;
- When applying the cream, you do not need to rub it in; it is applied with patting movements;
- Can be used from age 25.
Remedial treatment for problem skin (pimples, acne, etc.) has proven itself well. Vitamins A and D have an anti-inflammatory effect and soothe the skin. Vitamin A helps restore skin. Vitamin D helps normalize skin metabolism. Vitamin E fights free radicals and improves skin condition.
Basics of application in this case:
- Apply twice a day (morning and evening) to inflamed areas of the skin;
- The maximum period of use is 6 weeks, then a break.
Radevit is used for dry and flaky lips. Due to the vitamins that make up the cream (A, D, E) and auxiliary components (vaseline, glycerin), hydration occurs.
When applying the cream to the lip area, you must consider:
- the cream is applied to the lips instead of medicated lipstick once a day;
- can be used as a lip mask: twice a week, apply the cream to your lips for a few minutes, then remove the excess with a napkin.
With any type of burn, the skin needs to be helped to recover. Thanks to its vitamin composition, Radevit copes well with this task.
When using burn cream you should know:
- Apply the composition to the “burnt” area once a day, preferably at night;
- if you have to go outside, the cream should be removed to avoid the effects of UF rays;
- In order for the skin to “breathe” you need to do without additional dressings.
The absence of hormones in the composition allows the cream to be used from a very early age. Children, including infants, can apply the cream for various dermatitis and skin problems.
When using, please consider:
- spread a thin layer on the problem area;
- Use no more than twice a day (after waking up in the morning and before going to bed in the evening).
Due to the possibility of oversaturation of the skin with vitamins, it is not recommended to use Radevit during pregnancy.
Pharmaceutical research and production enterprise
Registration number:
P N000330/01.
Trade name of the drug:
Radevit® Active.
Dosage form:
ointment for external use.
Compound:
- Active ingredients:
retinol palmitate (vitamin A) (in terms of 100% retinol palmitate) - 10 mg (composition per 1.0 g of substance: vitamin A palmitate 1.7 million IU, butylated hydroxyanisole 9 mg, butylated hydroxytoluene 9 mg or vitamin A palmitate 1.7 million IU, butylhydroxytoluene 17 mg, sunflower oil up to 1.0 g), alpha-tocopherol acetate (vitamin E) - 5 mg, colecalciferol (vitamin D3) - 0.05 mg (composition per 1.0 g of substance: vitamin D3 25 mg (1.0 million IU ), dl-alpha-tocopherol acetate 2.5 mg, triglycerides of fatty acids (medium chain length) 972.5 mg). - Excipients:
butylated hydroxytoluene 1.0 mg, butylated hydroxyanisole 1.0 mg, emulsion wax 80.0 mg, vaseline oil 50.0 mg, glycerol (glycerin) 100.0 mg, ethanol (ethyl alcohol 95%) 100.0 mg, purified water up to 1.0 g.
Description:
homogeneous ointment from white to light yellow.
Pharmacotherapeutic group:
dermatoprotective agent.
ATX code (D10AD).
Pharmacological properties
It has a reparative, anti-inflammatory and antipruritic effect, normalizes keratinization processes, and enhances the protective function of the skin.
Indications for use
Complex therapy for adults and children with ichthyosis and ichthyosiform dermatoses, seborrheic dermatitis, cracks, erosions and burns of the skin, uninfected wounds and ulcers, eczema, atopic dermatitis, neurodermatitis, allergic contact dermatitis (beyond the acute stage), psoriasis, dry skin.
Prevention of relapses of chronic inflammatory and allergic skin diseases, after cessation of treatment with glucocorticosteroids (in the subacute period), with easily irritated skin, including hypersensitivity to cosmetics.
Pregnancy and lactation
It is not recommended to apply to large areas of skin during pregnancy and lactation.
Contraindications
Hypersensitivity to the components of the drug. Hypervitaminosis A, D, E, taking retinoids.
Directions for use and doses
Externally. The ointment is applied to the affected areas of the skin in a thin layer 2 times a day. If the skin is severely peeling, an occlusive dressing may be used. Before applying the ointment to cracks and other skin defects, they are pre-treated with antiseptics.
The duration of treatment depends on the location and severity of the process and can be several weeks.
Side effect
When used in the acute period - increased itching and erythema (in this case, the drug must be temporarily discontinued until the severity of the process decreases). Allergic reactions. To avoid overdose and the development of hypervitaminosis, it is not recommended to apply the drug to large surfaces of the skin (over 80%) for more than 6 weeks.
Interaction with other drugs
Should not be used in combination with other drugs containing retinoids, vitamins A, E and D (risk of hypervitaminosis A, E, D).
The effect of the ointment is weakened by the simultaneous administration of glucocorticosteroids.
The administration of salicylates and glucocorticosteroids reduces side effects.
Release form
Ointment for external use.
Aluminum tubes of 10, 15, 20 or 35 g. Together with instructions for use, they are placed in a cardboard pack.
Storage conditions
Store at a temperature not exceeding 8 °C. Keep out of the reach of children. Do not allow freezing.
Best before date
4 years. Do not use after the expiration date stated on the package.
Conditions for dispensing from pharmacies
Over the counter.
Radevit in complex treatment
Radevit is used not only as a single agent, but also as part of complex therapy. When fighting wrinkles, Radevit is often added to masks to enhance the effect. Many girls mix a small amount of ointment into their daily face cream. It is important to remember that you cannot combine Radevit with a cream or mask that already contains vitamins A, D, E, so as not to oversaturate the skin.
In the treatment of skin diseases, in addition to antihistamines, sorbents, Radevit is used topically as an anti-inflammatory and immunity-boosting drug. The cream, along with Bepanten, is used to treat diaper rash and dermatitis in infants.
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Contraindications for use
It is strictly forbidden to use the cream during pregnancy and breastfeeding.
In addition, sensitivity to certain components is also a contraindication. If the sebaceous glands are overactive and the content of vitamins is high, you should not use Radevit.
It is forbidden to apply ointment to open wounds as a medicinal preparation. Certain defects on the skin may indicate impaired functioning of the endocrine system and blood circulation. External treatment, in this case, will be powerless, since the reasons lie in the internal state of the body.
Also, do not apply cream to affected areas around which swelling or redness is noticeable. Perhaps we are talking about an infection, and antibiotics are used as therapeutic agents.
What result to expect
Radevit cream is widely used for various skin problems.
The effect of using the cream can be as follows:
- moisturizing for dry skin;
- improvement of skin condition: color, tone;
- small cracks are healed;
- when used during burns or allergic reactions, itching and irritation are reduced;
- the skin becomes silkier;
- restores skin;
- reduces the manifestation of allergic rashes.
Side effects
In some cases, an allergic reaction may develop, redness will appear on the skin near or directly on the treated area, and swelling rarely appears there and pain increases.
Overdose
Since the drug is designed for external use, intoxication of the body is completely excluded. There were no cases of ointment getting into the mouth or eyes.
Drug interactions
In order to prevent excess amounts of vitamins in the body (hypervitaminosis), it is advisable to avoid all other drugs that contain retinoids or vitamin components, especially A, E and D, for the duration of the treatment course.
The simultaneous use of hormonal agents also leads to a decrease in the effectiveness of the ointment. But to reduce existing or possible adverse reactions of the body, in some cases glucocorticosteroids and salicylates are prescribed.
Additional instructions
It is worth noting that pharmacies sell an almost similar ointment called Radevit asset. Many believe that this is the same drug, but Radevit active also contains vitamin D3 and completely excludes the presence of vitamin D2.
Price, storage conditions and shelf life
Radevit cream is a fairly common drug; it can be found in any pharmacy. The price will vary from 320 to 400 rubles. per tube 35 g.
Radevit face cream costs from 300 to 400 rubles in pharmacies.
The drug should be stored in a cool place at a temperature not exceeding 9 degrees. The cream should not be frozen; it loses its functions. An opened tube must be used within 2 years, otherwise it will become unusable.